I have hand tied for several years using Maxima and connecting the sections with blood knots. In recent years I have used the Davy Wotton leader knot. It is a strong knot and much smaller than a blood knot, I also use the Davy knot and double Davy knot for connecting the fly to the leader. It is fast to tie and stronger and smaller than a clinch knot.
If you google the Davy Wotton leader knot, there is a video on tying it, done by Troutpreditor, there are several videos on the Davy knot as well.
Nick